ISDA: 9P0K

Deposition Date 2025-06-06

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9P0K

Keywords:

MEMBRANE PROTEIN

Title:

Composite map of CXCL9-CXCR3-Gi-scFv16

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens, Escherichia coli, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.50 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:C-X-C chemokine receptor type
Gene (Uniprot):CXCR3, EAH_00062270
Chain IDs:A
Chain Length:684
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P49682,U6GSR1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:C-X-C motif chemokine 9
Chain IDs:B
Chain Length:103
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q07325

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Chain IDs:C
Chain Length:376
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63096

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:D
Chain Length:357
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:E
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:scFV16
Chain IDs:F
Chain Length:269
Number of Molecules:1
Biological Source:Mus musculus

UniProt ID:9P0K

Ligand Molecules

Primary Citation

Molecular basis of CXC chemokine receptor 3 ligand multispecificity.

Bouyssou, A, Sun, D, Zhou, T, Smith, S, Ho, H, Johnson, M, Azumaya, C, Noreng, S, Liu, P, Ti, S, Joshi, P, Tam, C, Yang, Y, Janezic, E, Comps-Agrar, L, Masureel, M.Show

Sci Adv 12 eadz3767 eadz3767 (2026)

PMID: 41996512 DOI: 10.1126/sciadv.adz3767

Primary Citation of related structures

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