9OU8 image
Deposition Date 2025-05-28
Release Date 2026-06-24
Last Version Date 2026-06-24
Entry Detail
PDB ID:
9OU8
Keywords:
OXIDOREDUCTASE
Title:
Crystal structure of hUGDH Dimer-A104L/A136M complexed with UDP-Xyl
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.41 Å
R-Value Free:
0.21
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
H 3
9OU8 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:UDP-glucose 6-dehydrogenase
Gene (Uniprot):UGDH
Mutagens:A104L, A136M, F323D, Deleted 324, T325D, T327V
Chain IDs:A, B
Chain Length:464
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:O60701 Pfam ID:PF03721, PF00984, PF03720 EC:1.1.1.22
Ligand Molecules
EDO
PO4
UDX
Primary Citation
Allostery and oligomerization control the nature of human UGDH core packing
To Be Published ? ? ? (?)
Primary Citation of related structures
9OU8
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