9OSX image
Deposition Date 2025-05-26
Release Date 2025-12-24
Last Version Date 2026-03-25
Entry Detail
PDB ID:
9OSX
Keywords:
IMMUNE SYSTEM
Title:
PfCyRPA-EM epitope mimic bound to monoclonal antibody Cy.004
Biological Source:
Source Organism(s):
synthetic construct (Taxon ID: 32630)
Gallus gallus (Taxon ID: 9031)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.67 Å
R-Value Free:
0.29
R-Value Work:
0.25
R-Value Observed:
0.25
Space Group:
C 1 2 1
9OSX validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:PfCyRPA-EM
Chain IDs:A
Chain Length:131
Number of Molecules:1
Biological Source:synthetic construct
UniProt ID:9OSX
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cy.004 heavy chain
Chain IDs:B
Chain Length:321
Number of Molecules:1
Biological Source:Gallus gallus
UniProt ID:9OSX
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cy.004 light chain
Chain IDs:C
Chain Length:209
Number of Molecules:1
Biological Source:Gallus gallus
UniProt ID:9OSX
Primary Citation
Structure-guided design of a PfCyRPA-based vaccine against blood-stage malaria.
Embo Mol Med 18 873 890 (2026)
PMID: 41772083 DOI: 10.1038/s44321-026-00376-x
Primary Citation of related structures
9OSX
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