ISDA: 9OM5

Deposition Date 2025-05-13

Release Date 2026-05-27

Last Version Date 2026-05-27

Entry Detail

PDB ID:

9OM5

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

Composite map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemagglutinin

Biological Source:

Source Organism(s):

Influenza A virus (Taxon ID: 11320)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Gene (Uniprot):HA
Chain IDs:A, C, E
Chain Length:348
Number of Molecules:3
Biological Source:Influenza A virus

UniProt ID:A0A5P1MU07

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Gene (Uniprot):HA
Chain IDs:B, D, F
Chain Length:219
Number of Molecules:3
Biological Source:Influenza A virus

UniProt ID:A0A2P1E3C0

Protein Blast

Polymer Type:polypeptide(L)
Molecule:MEDI8852 Fab heavy chain
Chain IDs:G, I, K
Chain Length:222
Number of Molecules:3
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:MEDI8852 Fab light chain
Chain IDs:H, J, L
Chain Length:219
Number of Molecules:3
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:VRC35 Fab heavy chain
Chain IDs:M (auth: a), O (auth: c), Q (auth: e), S (auth: g), U (auth: i), W (auth: k)
Chain Length:348
Number of Molecules:6
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:VRC35 Fab light chain
Chain IDs:N (auth: b), P (auth: d), R (auth: f), T (auth: h), V (auth: j), X (auth: l)
Chain Length:219
Number of Molecules:6
Biological Source:Homo sapiens

Ligand Molecules