9OHM image
Deposition Date 2025-05-05
Release Date 2026-05-27
Last Version Date 2026-05-27
Entry Detail
PDB ID:
9OHM
Keywords:
SIGNALING PROTEIN
Title:
Cryo-EM structure of bovine phosphodiesterase 6 bound to CB-5083
Biological Source:
Source Organism(s):
Bos taurus (Taxon ID: 9913)
Expression System(s):
Bos taurus
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.72 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9OHM validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Rod cGMP-specific 3',5'-cycli
Gene (Uniprot):PDE6A
Chain IDs:A
Chain Length:859
Number of Molecules:1
Biological Source:Bos taurus
UniProt ID:P11541 Pfam ID:PF01590, PF00233 EC:3.1.4.35
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Rod cGMP-specific 3',5'-cycli
Gene (Uniprot):PDE6B
Chain IDs:B
Chain Length:853
Number of Molecules:1
Biological Source:Bos taurus
UniProt ID:P23439 Pfam ID:PF01590, PF00233 EC:3.1.4.35
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Retinal rod rhodopsin-sensiti
Gene (Uniprot):PDE6G
Chain IDs:C, D
Chain Length:87
Number of Molecules:2
Biological Source:Bos taurus
UniProt ID:P04972 Pfam ID:PF04868 EC:3.1.4.35
Ligand Molecules
JDP
MG
PCG
ZN
Primary Citation
Cryo-EM-guided subtractive optimization of a novel VCP/p97 inhibitor
To Be Published ? ? ? (?)
Primary Citation of related structures
9OHM
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