9OEG image
Deposition Date 2025-04-28
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
9OEG
Keywords:
Title:
Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2
Biological Source:
Source Organism(s):
Astrovirus VA1 (Taxon ID: 645687)
Mus musculus (Taxon ID: 10090)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.05 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Capsid polyprotein VP90
Gene (Uniprot):ORF2
Chain IDs:D (auth: A), E (auth: B)
Chain Length:289
Number of Molecules:2
Biological Source:Astrovirus VA1
Protein Blast
Polymer Type:polypeptide(L)
Molecule:2A2 heavy chain
Chain IDs:A (auth: H), F (auth: J)
Chain Length:224
Number of Molecules:2
Biological Source:Mus musculus
Protein Blast
Polymer Type:polypeptide(L)
Molecule:2A2 light chain
Chain IDs:B (auth: K), C (auth: L)
Chain Length:215
Number of Molecules:2
Biological Source:Mus musculus
Ligand Molecules
Primary Citation
Cryo-EM Structures of the Human Astrovirus VA1 Capsid Spike Bound to Neutralizing Antibodies: Implications for Therapeutic Strategies
To Be Published ? ? ? (?)
Primary Citation of related structures
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