9O7H image
Deposition Date 2025-04-15
Release Date 2026-05-13
Last Version Date 2026-05-13
Entry Detail
PDB ID:
9O7H
Keywords:
LIGASE/IMMUNE SYSTEM
Title:
CHIP E3 ligase dimer bound to 1 Fab 2D2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
4.80 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9O7H validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase C
Gene (Uniprot):STUB1
Chain IDs:A, B
Chain Length:281
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9UNE7 Pfam ID:PF12895, PF18391, PF04564 EC:2.3.2.27
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:2D2 Fab light chain
Chain IDs:C
Chain Length:214
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9O7H
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:2D2 Fab heavy chain
Chain IDs:D
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:9O7H
Ligand Molecules
NA
Primary Citation
Structures of Fab-stabilized CHIP reveal a conformational switch important in E3 ligase and chaperone functions
To Be Published ? ? ? (?)
Primary Citation of related structures
9O7H
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