ISDA: 9O36

Deposition Date 2025-04-05

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9O36

Keywords:

MEMBRANE PROTEIN

Title:

CryoEM structure of mu-opioid receptor - Gi protein complex bound to fluornitrazene (FNZ)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Trichoplusia ni, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Chain IDs:A
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63096 Pfam ID:PF00503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:344
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:D (auth: E)
Chain Length:259
Number of Molecules:1
Biological Source:Mus musculus

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Mu-type opioid receptor
Gene (Uniprot):Oprm1
Chain IDs:E (auth: R)
Chain Length:426
Number of Molecules:1
Biological Source:Mus musculus

UniProt ID:P42866 Pfam ID:PF00001

Ligand Molecules