ISDA: 9O1Q

Deposition Date 2025-04-03

Release Date 2026-05-06

Last Version Date 2026-05-06

Entry Detail

PDB ID:

9O1Q

Keywords:

LIPID TRANSPORT

Title:

TMEM16F D409G mutant in liposomes in the presence of Ca2+ (active state)

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.20 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Anoctamin-6
Gene (Uniprot):Ano6
Mutagens:D409G
Chain IDs:A, B
Chain Length:911
Number of Molecules:2
Biological Source:Mus musculus

UniProt ID:Q6P9J9 Pfam ID:PF16178, PF04547

Ligand Molecules

Primary Citation

CryoEM in vesicles reveals the Ca2+-dependent activation mechanism of the TMEM16F scramblase and ion channel

Feng, Z, Alvarenga, O.E, Di Zanni, E, Lee, S, Khelashvili, G, Accardi, A.Show

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Primary Citation of related structures

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