9O04 image
Deposition Date 2025-04-02
Release Date 2026-01-21
Last Version Date 2026-04-15
Entry Detail
PDB ID:
9O04
Keywords:
Title:
CryoEM structure of the FBXO42-CCDC6-PP2Ac degradasome
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Coiled-coil domain-containing
Gene (Uniprot):CCDC6
Chain IDs:A, B
Chain Length:490
Number of Molecules:2
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:F-box only protein 42
Gene (Uniprot):FBXO42
Chain IDs:C, G
Chain Length:691
Number of Molecules:2
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Serine/threonine-protein phos
Gene (Uniprot):PPP2CA
Chain IDs:D, E, I, J, K, L, M, N
Chain Length:336
Number of Molecules:8
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:SKP1
Chain IDs:F, H
Chain Length:151
Number of Molecules:2
Biological Source:Homo sapiens
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
MLL D LEU modified residue
Ligand Molecules
Primary Citation
Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation
Nature ? ? ? (2026)
DOI: 10.1038/s41586-026-10368-z
Primary Citation of related structures
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