ISDA: 9NX4

Deposition Date 2025-03-25

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9NX4

Keywords:

DNA BINDING PROTEIN

Title:

Crystal Structure of a P. Aeruginosa Gyrase Chimera In Complex with 20mer DNA and Ciprofloxacin

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa (Taxon ID: 287)
Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.85 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 63 2 2

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Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA gyrase subunit B,DNA gyra
Gene (Uniprot):gyrA, gyrB
Chain IDs:A
Chain Length:942
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa

UniProt ID:Q9S1C7,A0A2R3INH2

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*AP*GP*CP*CP*GP*TP*
Chain IDs:B (auth: C)
Chain Length:20
Number of Molecules:1
Biological Source:Escherichia coli

Ligand Molecules

CIT

CPF

SO4

Primary Citation

Structural and Computational Analysis of Pseudomonas aeruginosa DNA Gyrase Reveals Molecular Characteristics That May Contribute to Ciprofloxacin Resistance.

Perera, L, Garcia-Villada, L, Kaminski, A.M, Degtyareva, N, Pedersen, L.C, Doetsch, P.W.Show

Biomolecules 16 ? ? (2026)

PMID: 41750386 DOI: 10.3390/biom16020318

Primary Citation of related structures

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