9NSP image
Deposition Date 2025-03-17
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9NSP
Keywords:
VIRAL PROTEIN/DNA
Title:
MPXV replisome bound to ssDNA
Biological Source:
Source Organism(s):
Monkeypox virus (Taxon ID: 10244)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
4.10 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9NSP validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:DNA polymerase
Chain IDs:C (auth: A)
Chain Length:1006
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polypeptide(L)
Molecule:Uracil-DNA glycosylase
Chain IDs:E (auth: B)
Chain Length:218
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polypeptide(L)
Molecule:DNA polymerase processivity f
Chain IDs:D (auth: C)
Chain Length:426
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polypeptide(L)
Molecule:Uncoating factor OPG117
Chain IDs:A (auth: D), B (auth: E), G (auth: I), H, I (auth: J), J (auth: K)
Chain Length:785
Number of Molecules:6
Biological Source:Monkeypox virus
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*TP*TP*TP*TP*TP
Chain IDs:F (auth: T)
Chain Length:29
Number of Molecules:1
Biological Source:Monkeypox virus
Ligand Molecules
ZN
Primary Citation
Structure and operating principles of a monkeypox virus replisome
Nature ? ? ? (2026)
DOI: 10.1038/s41586-026-10937-2
Primary Citation of related structures
9NSP
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