9NP6 image
Deposition Date 2025-03-11
Release Date 2025-03-19
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9NP6
Keywords:
ISOMERASE/DNA
Title:
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and blunt end DNA
Biological Source:
Source Organism(s):
Mycolicibacterium smegmatis MC2 155 (Taxon ID: 246196)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Escherichia coli bl21
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.40 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9NP6 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA 3'-5' helicase
Gene (Uniprot):MSMEG_1941
Chain IDs:A
Chain Length:1046
Number of Molecules:1
Biological Source:Mycolicibacterium smegmatis MC2 155
UniProt ID:A0QTR9 Pfam ID:PF00580, PF13361, PF12705
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA 3'-5' helicase
Gene (Uniprot):MSMEI_1900
Chain IDs:B
Chain Length:1095
Number of Molecules:1
Biological Source:Mycolicibacterium smegmatis MC2 155
UniProt ID:I7FZ56 Pfam ID:PF00580, PF13361, PF12705
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (30-MER)
Chain IDs:C (auth: X)
Chain Length:59
Number of Molecules:1
Biological Source:synthetic construct
Ligand Molecules
ANP
SF4
Primary Citation
Structure of an initiation complex of mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals local melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor.
Nucleic Acids Res. 54 ? ? (2026)
PMID: 41854076 DOI: 10.1093/nar/gkag243
Primary Citation of related structures
6PPJ
6PPU
6PPR
7SJR
Feedback Form
Name
Email
Institute
Feedback