9NMT image
Deposition Date 2025-03-04
Release Date 2026-01-28
Last Version Date 2026-01-28
Entry Detail
PDB ID:
9NMT
Keywords:
MEMBRANE PROTEIN
Title:
ML418 bound inwardly rectifying potassium channel Kir7.1 R162Q mutant
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.90 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9NMT validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Inward rectifier potassium ch
Gene (Uniprot):KCNJ13
Mutagens:R162Q
Chain IDs:A, B, C, D
Chain Length:360
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:O60928 Pfam ID:PF01007, PF17655
Ligand Molecules
A1BY7
Primary Citation
ML418 Binds in the Pore of the Inward Rectifier Kir7.1 and Inhibits the Channel In Vivo to Reduce Food Intake and Body Weight
To be published ? ? ? (?)
Primary Citation of related structures
9NMT
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