ISDA: 9NGJ

Deposition Date 2025-02-22

Release Date 2025-12-17

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9NGJ

Keywords:

TRANSPORT PROTEIN

Title:

CryoEM structure of human ABCD3 bound to Phytanoyl-CoA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.13 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:ATP-binding cassette sub-fami
Gene (Uniprot):ABCD3
Chain IDs:A (auth: B), B (auth: A)
Chain Length:688
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P28288 Pfam ID:PF06472, PF00005 EC:7.6.2.4

Ligand Molecules

A1CAN

Primary Citation

Molecular mechanism of substrate transport by human peroxisomal ABCD3.

Gupta, M, Khandelwal, N.K, Seka, D.J, Balasubramani, S.G, Dickinson, M.S, Myasnikov, A, Echeverria, I, Stroud, R.M.Show

Proc.Natl.Acad.Sci.USA 122 e2513928122 e2513928122 (2025)

PMID: 41428872 DOI: 10.1073/pnas.2513928122

Primary Citation of related structures

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