ISDA: 9NFW

Deposition Date 2025-02-21

Release Date 2026-08-12

Last Version Date 2026-08-12

Entry Detail

PDB ID:

9NFW

Keywords:

GENE REGULATION

Title:

Human SRCAP-CFDP1-nucleosome complex in the activated state of the H2A.Z histone exchange reaction (composite structure)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Xenopus laevis (Taxon ID: 8355)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.80 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Helicase SRCAP
Chain IDs:A
Chain Length:3230
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Vacuolar protein sorting-asso
Chain IDs:B
Chain Length:364
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Actin-related protein 6
Chain IDs:C
Chain Length:396
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Zinc finger HIT domain-contai
Chain IDs:D
Chain Length:154
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:RuvB-like 1
Chain IDs:E, G, I
Chain Length:456
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:RuvB-like 2
Chain IDs:F, H, J
Chain Length:463
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Craniofacial development prot
Chain IDs:K (auth: P)
Chain Length:299
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1
Chain IDs:L (auth: Q), N (auth: S)
Chain Length:128
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H2B 1.1
Chain IDs:M (auth: R), O (auth: T)
Chain Length:125
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H3.2
Chain IDs:P (auth: U), R (auth: W)
Chain Length:135
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:Q (auth: V), S (auth: X)
Chain Length:102
Number of Molecules:2
Biological Source:Xenopus laevis

Polymer Type:polydeoxyribonucleotide
Molecule:DNA(285-MER)
Chain IDs:T (auth: Y)
Chain Length:285
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA(285-MER)
Chain IDs:U (auth: Z)
Chain Length:285
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules