ISDA: 9NCN

Deposition Date 2025-02-16

Release Date 2026-02-18

Last Version Date 2026-02-18

Entry Detail

PDB ID:

9NCN

Keywords:

SIGNALING PROTEIN

Title:

IN-ML-15 bound to IRzip

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Cricetulus griseus

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.86 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:IN-ML-15 beta
Chain IDs:A (auth: C), C (auth: D)
Chain Length:32
Number of Molecules:2
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform Short of Insulin rece
Chain IDs:E, F
Chain Length:930
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P06213 Pfam ID:PF01030, PF00757, PF00041, PF17870

Polymer Type:polypeptide(L)
Molecule:IN-ML-15
Chain IDs:B (auth: G), D (auth: H)
Chain Length:21
Number of Molecules:2
Biological Source:synthetic construct

Ligand Molecules

NAG

Primary Citation

IN-ML-15 bound to IRzip

Selicharova, I, Kirk, N.S, Lubos, M, Kertisova, A, Mitrova, K, Zakova, L, Chrudinova, M, Brezinova, J, Harant, K, Voldrich, J, Panikova, T, Torres-Aleman, I, Huffman, D, Jiracek, J.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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