9MNT image
Deposition Date 2024-12-23
Release Date 2026-01-14
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9MNT
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Structure of Hepatitis C virus envelope glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody RM1-73
Biological Source:
Source Organism(s):
Macaca mulatta (Taxon ID: 9544)
Recombinant Hepatitis C virus HK6a/JFH-1 (Taxon ID: 595609)
Expression System(s):
Homo sapiens, Unidentified
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.55 Å
R-Value Free:
0.25
R-Value Work:
0.23
R-Value Observed:
0.23
Space Group:
P 21 21 21
9MNT validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Hepatitis C virus envelope gl
Chain IDs:C (auth: E)
Chain Length:189
Number of Molecules:1
Biological Source:Recombinant Hepatitis C virus HK6a/JFH-1
Polymer Type:polypeptide(L)
Molecule:RM1-73 Fab heavy chain
Chain IDs:B (auth: H)
Chain Length:235
Number of Molecules:1
Biological Source:Macaca mulatta
Polymer Type:polypeptide(L)
Molecule:RM1-73 Fab light chain
Chain IDs:A (auth: L)
Chain Length:212
Number of Molecules:1
Biological Source:Macaca mulatta
Ligand Molecules
NAG
SO4
Primary Citation
Structural and genetic signatures of two classes of HCV E2 neutralizing face antibodies from non-human primates immunized with a recombinant E1E2.
Npj Vaccines ? ? ? (2026)
PMID: 42009696 DOI: 10.1038/s41541-026-01449-1
Primary Citation of related structures
9MNT
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