9MCM image
Deposition Date 2025-03-17
Release Date 2026-09-23
Last Version Date 2026-09-23
Entry Detail
PDB ID:
9MCM
Keywords:
VIRAL PROTEIN
Title:
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with Leritrelvir
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.96 Å
R-Value Free:
0.25
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 21 21 21
9MCM validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:3C-like proteinase nsp5
Gene (Uniprot):rep
Mutagens:P3359H
Chain IDs:A, B
Chain Length:294
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTD1 Pfam ID:PF05409 EC:2.7.7.48
Ligand Molecules
A1EN0
Primary Citation
Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with Leritrelvir
To Be Published ? ? ? (?)
Primary Citation of related structures
9MCM
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