9M8L image
Deposition Date 2025-03-12
Release Date 2026-03-18
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9M8L
Title:
cryo-EM structure of human TAS2R4
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:E (auth: A)
Chain Length:239
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB3
Chain IDs:D (auth: B)
Chain Length:351
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG13
Chain IDs:C (auth: G)
Chain Length:67
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Single-chain variable fragmen
Chain IDs:B (auth: N)
Chain Length:307
Number of Molecules:1
Biological Source:Mus musculus
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Taste receptor type 2 member
Gene (Uniprot):TAS2R4
Chain IDs:A (auth: R)
Chain Length:337
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Receptor hyper-flexibility for detecting diverse bitter tastes revealed by the significant structural rearrangements in human bitter taste receptor TAS2R4
To be published ? ? ? (?)
Primary Citation of related structures
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