ISDA: 9M0U

Deposition Date 2025-02-25

Release Date 2026-01-14

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9M0U

Keywords:

OXIDOREDUCTASE

Title:

Structural insights into the tumor suppressor ZMYND11 reveal diverse recognition mechanisms

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Prokaryote coculture

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.89 Å

R-Value Free:

0.23

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

H 3 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Zinc finger MYND domain-conta
Gene (Uniprot):ZMYND11
Chain IDs:A, B
Chain Length:62
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q15326

Ligand Molecules

ACT

MPD

Primary Citation

Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets.

Bai, X, Zhang, J, Wang, S, Huang, K, Pan, Z, Liang, A, Wu, W, Yu, Z, Chen, Y, Tong, Y, Dai, S, Chen, Z.Show

Nucleic Acids Res. 54 ? ? (2026)

PMID: 41591843 DOI: 10.1093/nar/gkag048

Primary Citation of related structures

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