ISDA: 9LXR

Deposition Date 2025-02-19

Release Date 2025-09-10

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9LXR

Keywords:

MEMBRANE PROTEIN

Title:

A Cryo-EM structure of LA-PTH-PTH1R-Beta-arrestin1 complex (state 1 conformation)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.07 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-arrestin-1
Gene (Uniprot):ARRB1
Chain IDs:A (auth: B)
Chain Length:374
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P49407 Pfam ID:PF00339, PF02752

Polymer Type:polypeptide(L)
Molecule:Fab30H
Chain IDs:B (auth: C)
Chain Length:230
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polypeptide(L)
Molecule:Fab30L
Chain IDs:C (auth: E)
Chain Length:215
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:LA-PTH
Chain IDs:D (auth: L)
Chain Length:36
Number of Molecules:1
Biological Source:synthetic construct

UniProt ID:F5GZD9 Pfam ID:PF01279

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Parathyroid hormone/parathyro
Gene (Uniprot):PTH1R
Chain IDs:E (auth: R)
Chain Length:482
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q03431 Pfam ID:PF02793, PF00002

Modified Residue