9LTG image
Deposition Date 2025-02-06
Release Date 2026-08-12
Last Version Date 2026-08-12
Entry Detail
PDB ID:
9LTG
Keywords:
IMMUNE SYSTEM
Title:
Crystal structure of H-2Kb with C.parvum peptide
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Cryptosporidium parvum (Taxon ID: 5807)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.53 Å
R-Value Free:
0.27
R-Value Work:
0.22
Space Group:
P 1
9LTG validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:H-2 class I histocompatibilit
Chain IDs:A, B, C, D
Chain Length:276
Number of Molecules:4
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Chain IDs:E, F, G, H
Chain Length:99
Number of Molecules:4
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:PHE-LEU-PHE-LEU-PHE-GLU-ASN-V
Chain IDs:I, J, K, L
Chain Length:8
Number of Molecules:4
Biological Source:Cryptosporidium parvum
Ligand Molecules
EDO
Primary Citation
Structural basis for the lack of immunogenicity of a Cryptosporidium octapeptide: anchor switching induces MHC-I groove remodeling and instability.
Int.J.Biol.Macromol. 375 153155 153155 (2026)
PMID: 42336019 DOI: 10.1016/j.ijbiomac.2026.153155
Primary Citation of related structures
9LTG
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