9LQI image
Deposition Date 2025-01-28
Release Date 2026-08-05
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9LQI
Keywords:
IMMUNE SYSTEM
Title:
Structure of Nanobody-161 in complex of Tumor necrosis factor receptor 2 (TNFR2)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Vicugna pacos (Taxon ID: 30538)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.95 Å
R-Value Free:
0.29
R-Value Work:
0.26
R-Value Observed:
0.26
Space Group:
P 21 21 21
9LQI validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Nanobody-161 (B chain)
Chain IDs:A (auth: B), D (auth: A)
Chain Length:121
Number of Molecules:2
Biological Source:Vicugna pacos
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Tumor necrosis factor recepto
Gene (Uniprot):TNFRSF1B
Chain IDs:B (auth: R), C
Chain Length:235
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P20333 Pfam ID:PF00020
Ligand Molecules
NA
Primary Citation
Structure of Nanobody-161 in complex of Tumor necrosis factor receptor 2 (TNFR2) reveals a non-blocking mechanism for cancer therap
To Be Published ? ? ? (?)
Primary Citation of related structures
9LQI
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