9LJG image
Deposition Date 2025-01-15
Release Date 2025-12-03
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9LJG
Keywords:
TRANSPORT PROTEIN
Title:
Cryo-EM structure of human organic solute transporter OSTalpha/beta in apo state
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.64 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9LJG validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Organic solute transporter su
Gene (Uniprot):SLC51A
Chain IDs:A, C
Chain Length:340
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q86UW1 Pfam ID:PF03619
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Organic solute transporter su
Gene (Uniprot):SLC51B
Chain IDs:B, D
Chain Length:128
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q86UW2 Pfam ID:PF15048
Ligand Molecules
LBN
PLM
Y01
Primary Citation
Structure and mechanism of the human bile acid transporter OST alpha-OST beta.
Nature 651 251 259 (2026)
PMID: 41606314 DOI: 10.1038/s41586-025-09934-8
Primary Citation of related structures
9LJG
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