9LD2 image
Deposition Date 2025-01-05
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9LD2
Title:
Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab (focused refinement of the S2-76E1)
Biological Source:
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.73 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Gene (Uniprot):S
Chain IDs:A, D (auth: B), G (auth: C)
Chain Length:1288
Number of Molecules:3
Biological Source:Severe acute respiratory syndrome coronavirus 2
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:heavy chain of 76E1 Fab
Chain IDs:B (auth: G), E (auth: I), H (auth: K)
Chain Length:221
Number of Molecules:3
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:light chain of 76E1 Fab
Chain IDs:C (auth: H), F (auth: J), I (auth: L)
Chain Length:216
Number of Molecules:3
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab (focused refinement of the S2-76E1)
To Be Published ? ? ? (?)
Primary Citation of related structures
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