ISDA: 9LBQ

Deposition Date 2025-01-03

Release Date 2026-07-01

Last Version Date 2026-07-01

Entry Detail

PDB ID:

9LBQ

Keywords:

ANTIVIRAL PROTEIN/RNA/DNA

Title:

Cryo-EM structure of the Retron-Eco8 complex

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.94 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Retron Eco8 reverse transcrip
Gene (Uniprot):ret
Chain IDs:A, E, I, M
Chain Length:374
Number of Molecules:4
Biological Source:Escherichia coli

UniProt ID:P0DV59 EC:2.7.7.49

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Retron Eco8 OLD nuclease
Gene (Uniprot):old
Chain IDs:B, F, J, N
Chain Length:750
Number of Molecules:4
Biological Source:Escherichia coli

UniProt ID:P0DV58 EC:3.1.-.-

Polymer Type:polyribonucleotide
Molecule:RNA (83-MER)
Chain IDs:C, G, K, O
Chain Length:83
Number of Molecules:4
Biological Source:Escherichia coli

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (75-MER)
Chain IDs:D, H, L, P
Chain Length:75
Number of Molecules:4
Biological Source:Escherichia coli

Ligand Molecules

Primary Citation

Retron-Eco8 forms a heterotetramer complex to protects bacteria from phage infection

Jia, N, Zhang, J.T, Ji, C.G.Show

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Primary Citation of related structures

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