ISDA: 9L87

Deposition Date 2024-12-27

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9L87

Keywords:

IMMUNE SYSTEM/DNA

Title:

Structure of fish TREX1-DNA complex

Biological Source:

Source Organism(s):

Labeo rohita (Taxon ID: 84645)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.99 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

I 2 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:exodeoxyribonuclease III
Chain IDs:A (auth: B), B (auth: A)
Chain Length:196
Number of Molecules:2
Biological Source:Labeo rohita

UniProt ID:A0A498LXZ6

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*GP*TP*TP*GP*GP*CP*
Chain IDs:C (auth: F)
Chain Length:22
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

Distinct recognition pattern for double-stranded DNA allows TREX1 to maintain immune homeostasis

Zhu, J, Wang, L, Lin, C, Zhou, W.Show

Immunity ? ? ? (2026)

Primary Citation of related structures

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