ISDA: 9L7F

Deposition Date 2024-12-27

Release Date 2025-12-31

Last Version Date 2025-12-31

Entry Detail

PDB ID:

9L7F

Keywords:

HYDROLASE

Title:

Metallo Beta-Lactamase VIM-2 in complex with Dual MBL/SBL inhibitor B34

Biological Source:

Source Organism(s):

Escherichia coli BL21(DE3) (Taxon ID: 469008)

Expression System(s):

Klebsiella pneumoniae

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.50 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Metallo-beta-lactamase VIM-2
Gene (Uniprot):VIM-2
Chain IDs:A, B
Chain Length:232
Number of Molecules:2
Biological Source:Escherichia coli BL21(DE3)

UniProt ID:Q5U7L7 Pfam ID:PF00753

Ligand Molecules

A1EJI

GOL

Primary Citation

A class of novel, potent,dual-acting benzoquinte-borate Beta-lactamase inhibitors targeting SBL/MBL

Li, G.-B, Liang, G.-Q.Show

To be published ? ? ? (?)

Primary Citation of related structures

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