ISDA: 9L1E

Deposition Date 2024-12-14

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9L1E

Keywords:

TRANSPORT PROTEIN

Title:

Structure of piperidine-4-sulfonic acid-bound human Taurine Transporter in the inward-occluded conformation

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.82 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sodium- and chloride-dependen
Gene (Uniprot):SLC6A6
Chain IDs:A
Chain Length:620
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P31641 Pfam ID:PF00209

Ligand Molecules

A1EBD

Y01

Primary Citation

Structural mechanism of substrate binding and inhibition of human taurine transporter.

Qi, Y, Zhang, Y, Wang, D, Liu, J, Zhou, Y, Ji, W, Chen, X, Liu, L, Wang, R, Wu, J.X.Show

Nat Commun ? ? ? (2026)

PMID: 41857056 DOI: 10.1038/s41467-026-70772-x

Primary Citation of related structures

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