ISDA: 9L06

Deposition Date 2024-12-11

Release Date 2026-06-17

Last Version Date 2026-06-17

Entry Detail

PDB ID:

9L06

Keywords:

DNA BINDING PROTEIN

Title:

The cryo-EM structure of ATRX in complex with the nucleosome in the ADP.BeFx-bound state (composite)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Histone H3.3
Chain IDs:A, E
Chain Length:136
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:B
Chain Length:87
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1-C
Chain IDs:C, G
Chain Length:130
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H2B type 1-C/E/F/G/I
Chain IDs:D, H
Chain Length:126
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:F
Chain Length:86
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (207-MER)
Chain IDs:I
Chain Length:207
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (207-MER)
Chain IDs:J
Chain Length:207
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Transcriptional regulator ATR
Chain IDs:K
Chain Length:1260
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

ADP

Primary Citation

Mechanistic insights into chromatin modulation by the orphan remodeler ATRX

Zhou, K, Liu, Y.Show

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