9KOG image
Deposition Date 2024-11-20
Release Date 2026-06-17
Last Version Date 2026-06-17
Entry Detail
PDB ID:
9KOG
Keywords:
GENE REGULATION
Title:
Structure of human PRC2 with C36 compound
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.59 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9KOG validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone-lysine N-methyltransf
Gene (Uniprot):EZH2
Chain IDs:A
Chain Length:754
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q15910 Pfam ID:PF11616, PF18118, PF21358, PF18264, PF00856 EC:2.1.1.356
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Polycomb protein SUZ12
Gene (Uniprot):SUZ12
Chain IDs:C
Chain Length:600
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q15022 Pfam ID:PF23320, PF09733
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Polycomb protein EED
Gene (Uniprot):EED
Chain IDs:B (auth: D)
Chain Length:448
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O75530 Pfam ID:PF00400
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Zinc finger protein AEBP2
Gene (Uniprot):AEBP2
Chain IDs:D (auth: F)
Chain Length:106
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q6ZN18 Pfam ID:PF26014
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Histone-binding protein RBBP4
Gene (Uniprot):RBBP4
Chain IDs:E (auth: H)
Chain Length:407
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q09028 Pfam ID:PF12265, PF00400
Ligand Molecules
A1EGC
Primary Citation
Structure of human PRC2 with SAH and H3K27me3 peptide
To Be Published ? ? ? (?)
Primary Citation of related structures
9KOG
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