ISDA: 9K8O

Deposition Date 2024-10-24

Release Date 2025-10-29

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9K8O

Keywords:

DNA-RNA HYBRID

Title:

Crystal structure of a short zinc-dependent DNAzyme minGAA

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.04 Å

R-Value Free:

0.29

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 2 21 21

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Macromolecular Entities

Polymer Type:polydeoxyribonucleotide
Molecule:DNAzyme minGAA, catalytic str
Chain IDs:A, C, E, G
Chain Length:10
Number of Molecules:4
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide/polyribonucleotide hybrid
Molecule:substrate strand for DNAzyme
Chain IDs:B, D, F, H
Chain Length:11
Number of Molecules:4
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

A minimal RNA-cleaving DNAzyme and its catalytic mechanism.

Yamasaki, K, Inomata, R, Yamasaki, T, Kubota, T, Miyashita, N, Takeuchi, K, Miyagishi, M.Show

Nucleic Acids Res. 54 ? ? (2026)

PMID: 41538318 DOI: 10.1093/nar/gkaf1502

Primary Citation of related structures

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