9K22 image
Deposition Date 2024-10-16
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9K22
Title:
A novel histone H3K27 reader, CBFA2T2, inhibits H3K27me3 demethylation and tumor growth by regulating metabolic genes and metabolite levels
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.81 Å
R-Value Free:
0.29
R-Value Work:
0.24
R-Value Observed:
0.25
Space Group:
P 42 21 2
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein CBFA2T2
Gene (Uniprot):Cbfa2t2
Chain IDs:A, B (auth: C)
Chain Length:72
Number of Molecules:2
Biological Source:Mus musculus
Ligand Molecules
Primary Citation
A novel histone H3K27 reader, CBFA2T2, inhibits H3K27me3 demethylation and tumor growth by regulating metabolic genes and metabolite levels.
To be published ? ? ? (?)
Primary Citation of related structures
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