ISDA: 9JIC

Deposition Date 2024-09-11

Release Date 2025-12-17

Last Version Date 2025-12-17

Entry Detail

PDB ID:

9JIC

Keywords:

MEMBRANE PROTEIN/IMMUNE SYSTEM

Title:

Cryo-EM Structure of the apo HCAR3-Gi complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hydroxycarboxylic acid recept
Gene (Uniprot):HCAR3
Chain IDs:A
Chain Length:387
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P49019 Pfam ID:PF00001

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:C (auth: B)
Chain Length:337
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF00400, PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Mutagens:G203A,A326S
Chain IDs:B (auth: C)
Chain Length:351
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63096 Pfam ID:PF00503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:D (auth: G)
Chain Length:56
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Protein Blast

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:E (auth: S)
Chain Length:233
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Cryo-EM structure of apo HCAR3-Gi

Fang, Y, Fang, Y.Show

To be published ? ? ? (?)

Primary Citation of related structures

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