ISDA: 9I43

Deposition Date 2025-01-24

Release Date 2026-02-04

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9I43

Keywords:

ANTIVIRAL PROTEIN

Title:

Structure of anti-EV71 human monoclonal antibody 16-2-9D Fab

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.18 Å

R-Value Free:

0.17

R-Value Work:

0.14

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:heavy chain
Chain IDs:A (auth: H)
Chain Length:245
Number of Molecules:1
Biological Source:Homo sapiens

Protein Blast

Polymer Type:polypeptide(L)
Molecule:light chain
Chain IDs:B (auth: L)
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

EDO

Primary Citation

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71

Zhou, D, Kotecha, A, Kelly, J.T, Huang, P, Chen, Y, Walter, T.S, Duyvesteyn, H.M.E, Owens, R.J, Ho, S, Lin, T, Fry, E.E, Ren, J, Huang, K, Stuart, D.I.Show

Science Advances ? ? ? (2026)

Primary Citation of related structures

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