ISDA: 9HXU

Deposition Date 2025-01-08

Release Date 2026-01-14

Last Version Date 2026-01-14

Entry Detail

PDB ID:

9HXU

Keywords:

TRANSFERASE

Title:

Protein kinase CK2 catalytic subunit alpha (CSNK2A1 gene product) in complex with F2X-Entry screen fragment C02

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.20 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 43 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Casein kinase II subunit alph
Gene (Uniprot):CSNK2A1
Chain IDs:A, B
Chain Length:355
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P68400 Pfam ID:PF00069 EC:2.7.11.1

Ligand Molecules

SO4

SYA

Primary Citation

Crystallographic Fragment Screening with CK2 alpha', an Isoform of Human Protein Kinase CK2 Catalytic Subunit, and Its Use to Obtain a CK2 alpha'/Heparin Complex Structure

Werner, C, Barthel, T, Harasimowicz, H, Marminon, C, Weiss, M.S, Borgne, M.L, Niefind, K.Show

Kinases Phosphatases 4 1 ? (2026)

DOI: 10.3390/kinasesphosphatases4010001

Primary Citation of related structures

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