ISDA: 9HXG

Deposition Date 2025-01-07

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9HXG

Keywords:

RNA BINDING PROTEIN

Title:

Bacterial antiviral defense protein Ec2ApeA from Escherichia coli strain 2-156-04_S4_C1 saturated with pdCpdG dinucleotide (HEPN active site mutant R502A)

Biological Source:

Source Organism(s):

Escherichia coli 2-156-04_S4_C1 (Taxon ID: 1444203)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.43 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Bacterial antiviral defense p
Mutagens:R502A
Chain IDs:A, C, E, G, I, K, M, O, Q, S
Chain Length:593
Number of Molecules:10
Biological Source:Escherichia coli 2-156-04_S4_C1

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*CP*G)-3')
Chain IDs:B, D, F, H, J, L, N, P, R, T
Chain Length:2
Number of Molecules:10
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

ApeA is a deoxyribodinucleotide binding antiviral defense system targeting tRNA

Juozapaitis, J, Silanskas, A, Ruksenaite, A, Puteikiene, R, Truncaite, L, Songailiene, I, Tamulaitiene, G, Siksnys, V, Sasnauskas, G.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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