9HOM image
Deposition Date 2024-12-12
Release Date 2026-06-24
Last Version Date 2026-06-24
Entry Detail
PDB ID:
9HOM
Keywords:
LYASE
Title:
Variant H283N of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in complex with the product UMP and carbon dioxide at 1.1 Angstrom resolution
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.10 Å
R-Value Free:
0.14
R-Value Work:
0.12
R-Value Observed:
0.12
Space Group:
C 2 2 21
9HOM validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Uridine 5'-monophosphate synt
Gene (Uniprot):UMPS
Mutagens:H283N
Chain IDs:A
Chain Length:258
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P11172 Pfam ID:PF00215 EC:4.1.1.23
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
CSS A CYS modified residue
Ligand Molecules
CO2
PRO
SO4
U5P
Primary Citation
Variant H283N of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in complex with the product UMP and carbon dioxide at 1.1 Angstrom resolution
To Be Published ? ? ? (?)
Primary Citation of related structures
9HOM
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