ISDA: 9HO9

Deposition Date 2024-12-12

Release Date 2026-06-24

Last Version Date 2026-06-24

Entry Detail

PDB ID:

9HO9

Keywords:

LYASE

Title:

Variant D259N of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in resting state

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.30 Å

R-Value Free:

0.18

R-Value Work:

0.15

R-Value Observed:

0.16

Space Group:

C 2 2 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Uridine 5'-monophosphate synt
Gene (Uniprot):UMPS
Mutagens:D259N
Chain IDs:A
Chain Length:258
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P11172 Pfam ID:PF00215 EC:4.1.1.23

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
CSS	A	CYS	modified residue

Ligand Molecules

PRO

SO4

Primary Citation

Variant D259N of Orotidine 5'-monophosphate decarboxylase-domain of human UMPS in resting state

Kirck, L.L, Tittmann, K.Show

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Primary Citation of related structures

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