ISDA: 9HMD

Deposition Date 2024-12-09

Release Date 2025-12-24

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9HMD

Keywords:

LIPID BINDING PROTEIN

Title:

Crystal structure of PDE6D in complex with DeltaTag (6a)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.50 Å

R-Value Free:

0.28

R-Value Work:

0.23

R-Value Observed:

0.24

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Retinal rod rhodopsin-sensiti
Gene (Uniprot):PDE6D
Chain IDs:A, B
Chain Length:156
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O43924 Pfam ID:PF05351

Ligand Molecules

A1IWD

Primary Citation

Covalent modification of a glutamic acid inspired by HaloTag technology.

Zhang, R, Liu, J, Gasper, R, Unger, A, Kaschani, F, Kaiser, M, Janning, P, Waldmann, H.Show

Nat Commun 17 1257 1257 (2026)

PMID: 41617704 DOI: 10.1038/s41467-026-68999-9

Primary Citation of related structures

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