9HM1 image
Deposition Date 2024-12-06
Release Date 2026-06-17
Last Version Date 2026-06-17
Entry Detail
PDB ID:
9HM1
Keywords:
TRANSFERASE
Title:
Crystal structure of GSK3b in complex with N-(4-{5-[(2-aminoethyl)sulfamoyl]thiophen-2-yl}pyridin-2-yl)cyclopropanecarboxamide inhibitor
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.45 Å
R-Value Free:
0.26
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
P 32 2 1
9HM1 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Glycogen synthase kinase-3 be
Gene (Uniprot):GSK3B
Chain IDs:A
Chain Length:364
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P49841 Pfam ID:PF00069 EC:2.7.11.26
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR A TYR modified residue
Ligand Molecules
A1IV9
Primary Citation
Crystal structure of GSK3b in complex with N-(4-{5-[(2-aminoethyl)sulfamoyl]thiophen-2-yl}pyridin-2-yl)cyclopropanecarboxamide inhibitor
To Be Published ? ? ? (?)
Primary Citation of related structures
9HM1
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