ISDA: 9HJP

Deposition Date 2024-11-29

Release Date 2025-10-01

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9HJP

Keywords:

IMMUNE SYSTEM

Title:

Improved structure of mouse Gasdermin D

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Escherichia coli 0.1288

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.64 Å

R-Value Free:

0.25

R-Value Work:

0.23

R-Value Observed:

0.23

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gasdermin-D
Gene (Uniprot):Gsdmd
Chain IDs:A, B
Chain Length:452
Number of Molecules:2
Biological Source:Mus musculus

UniProt ID:Q9D8T2 Pfam ID:PF04598, PF17708

Ligand Molecules

PE8

Primary Citation

Improved structure of mouse gasdermin D: a new blueprint for structure-based drug design.

De Colibus, L, Ludzia, P, Biasutto, A, Pica, A, Hopper, J.T.S, Jazayeri, A, Durr, K.L.Show

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 81 408 415 (2025)

PMID: 40906124 DOI: 10.1107/S2053230X25007149

Primary Citation of related structures

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