ISDA: 9GZD

Deposition Date 2024-10-03

Release Date 2026-04-15

Last Version Date 2026-04-15

Entry Detail

PDB ID:

9GZD

Keywords:

DNA BINDING PROTEIN

Title:

Androgen Receptor ligand-binding domain in complex with 11-ketodihydrotestosterone

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.91 Å

R-Value Free:

0.25

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Androgen receptor
Gene (Uniprot):AR
Chain IDs:A
Chain Length:249
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P10275 Pfam ID:PF00104

Ligand Molecules

A1IQ9

GOL

IMD

SO4

SPD

Primary Citation

Multi-omics and structural analyses on Androgen Receptor reveals highly similar biological actions of testosterone variants from testicular versus adrenal origins in prostate cancer cells

Minnee, E, Lacoste, A, Alegre-Marti, A, Gregoricchio, S, Fuentes-Prior, P, van der Zande, K, van Herwaarden, T, Estebanez-Perpina, E, Bergman, A.M, Zwart, W.Show

To be published ? ? ? (?)

Primary Citation of related structures

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