ISDA: 9GCP

Deposition Date 2024-08-02

Release Date 2025-08-13

Last Version Date 2025-08-13

Entry Detail

PDB ID:

9GCP

Keywords:

TRANSCRIPTION

Title:

ChREBP/14-3-3 complex stabilized by AMP

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.59 Å

R-Value Free:

0.27

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:14-3-3 protein beta/alpha, N-
Gene (Uniprot):YWHAB
Chain IDs:A, C, E, G
Chain Length:230
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P31946 Pfam ID:PF00244

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Carbohydrate-responsive eleme
Gene (Uniprot):MLXIPL
Chain IDs:B, D, F, H
Chain Length:20
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q9NP71

Ligand Molecules

AMP

Primary Citation

Glucose-6-phosphate functions as a selective receptor agonist for the sugar tolerance transcription factor ChREBP

Moschref, M, Heimhalt, M, Pysik, T, Menzer, W.M, Basquin, J, Margulies, C.E, Ladurner, A.G.Show

To be published ? ? ? (?)

Primary Citation of related structures

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