ISDA: 9G6W

Deposition Date 2024-07-19

Release Date 2025-07-30

Last Version Date 2026-09-16

Entry Detail

PDB ID:

9G6W

Keywords:

SUGAR BINDING PROTEIN

Title:

L-SIGN CRD in complex with Man96.

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.28

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 65

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform 1 of C-type lectin do
Gene (Uniprot):CLEC4M
Chain IDs:A, B
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9H2X3 Pfam ID:PF00059

Ligand Molecules

A1IIW

TRS

Primary Citation

Increasing the Chemical Space of L-SIGN Specific Glycomimetics.

Cavazzoli, G, Delaunay, C, Pollastri, S, Panzeri, A, Sattin, S, Thepaut, M, Belvisi, L, Fieschi, F, Bernardi, A.Show

J.Med.Chem. 68 22530 22546 (2025)

PMID: 41108276 DOI: 10.1021/acs.jmedchem.5c01448

Primary Citation of related structures

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