ISDA: 9EK4

Deposition Date 2024-11-30

Release Date 2026-06-24

Last Version Date 2026-06-24

Entry Detail

PDB ID:

9EK4

Keywords:

IMMUNE SYSTEM

Title:

Crystal structure of HLA-B*07:02 with the 9-mer TP53 mutant peptide MPILTIITL

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.05 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:HLA class I histocompatibilit
Gene (Uniprot):HLA-B
Chain IDs:A, D
Chain Length:277
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P01889 Pfam ID:PF00129, PF07654

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:B, E
Chain Length:100
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P61769 Pfam ID:PF07654

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Mutant peptide from Cellular
Gene (Uniprot):TP53
Mutagens:R249M (Uniprot numbering)
Chain IDs:C, F
Chain Length:9
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P04637

Ligand Molecules