9ECE image
Deposition Date 2024-11-14
Release Date 2025-11-19
Last Version Date 2026-09-02
Entry Detail
PDB ID:
9ECE
Keywords:
RNA BINDING PROTEIN/RNA
Title:
Inactive state of wild-type EsCas13d ternary complex with C4A mismatch
Biological Source:
Source Organism(s):
[Eubacterium] siraeum DSM 15702 (Taxon ID: 428128)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.01 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9ECE validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:EsCas13d
Gene (Uniprot):EUBSIR_02687
Chain IDs:A
Chain Length:954
Number of Molecules:1
Biological Source:[Eubacterium] siraeum DSM 15702
UniProt ID:B0MS50
Polymer Type:polyribonucleotide
Molecule:crRNA
Chain IDs:B
Chain Length:52
Number of Molecules:1
Biological Source:[Eubacterium] siraeum DSM 15702
Polymer Type:polyribonucleotide
Molecule:Target RNA with C4A mismatch
Chain IDs:C
Chain Length:30
Number of Molecules:1
Biological Source:[Eubacterium] siraeum DSM 15702
Ligand Molecules
MG
Primary Citation
Structural basis for target discrimination and activation by Cas13d.
Sci Adv 12 eaec4221 eaec4221 (2026)
PMID: 42616864 DOI: 10.1126/sciadv.aec4221
Primary Citation of related structures
9ECE
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