ISDA: 9EBU

Deposition Date 2024-11-13

Release Date 2025-11-19

Last Version Date 2026-09-02

Entry Detail

PDB ID:

9EBU

Keywords:

RNA BINDING PROTEIN/RNA

Title:

Wild-type EsCas13d binary complex

Biological Source:

Source Organism(s):

[Eubacterium] siraeum DSM 15702 (Taxon ID: 428128)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.06 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:EsCas13d
Gene (Uniprot):EUBSIR_02687
Chain IDs:A
Chain Length:954
Number of Molecules:1
Biological Source:[Eubacterium] siraeum DSM 15702

UniProt ID:B0MS50

Polymer Type:polyribonucleotide
Molecule:crRNA
Chain IDs:B
Chain Length:52
Number of Molecules:1
Biological Source:[Eubacterium] siraeum DSM 15702

Ligand Molecules

Primary Citation

Structural basis for target discrimination and activation by Cas13d.

Chou, C.W, Sinan, S, Kuo, H.C, Chang, Y.C, Arguello, C, Sahaya, D, Russell, R, Finkelstein, I.J.Show

Sci Adv 12 eaec4221 eaec4221 (2026)

PMID: 42616864 DOI: 10.1126/sciadv.aec4221

Primary Citation of related structures

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