ISDA: 9E4E

Deposition Date 2024-10-24

Release Date 2026-01-21

Last Version Date 2026-07-29

Entry Detail

PDB ID:

9E4E

Keywords:

MEMBRANE PROTEIN

Title:

Human ASIC1a at pH 6.5 with linear transmembrane domain

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.16 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Acid-sensing ion channel 1
Gene (Uniprot):ASIC1
Chain IDs:A, B, C
Chain Length:531
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:P78348 Pfam ID:PF00858

Ligand Molecules

Primary Citation

Conformational plasticity of human acid-sensing ion channel 1a.

Cahill, J, Hartfield, K.A, Heusser, S.A, Ritter, N, Poulsen, M.H, Yoshioka, C, Pless, S.A, Baconguis, I.Show

Nat.Struct.Mol.Biol. ? ? ? (2026)

PMID: 42463865 DOI: 10.1038/s41594-026-01845-0

Primary Citation of related structures

Feedback Form